The predecessor of the Valley of Hope Art Gallery was Travers School, founded in 1933, later renamed Harapan School (Sekolah Harapan). However, after the closure of the school in 1975, following the graduation of all students, it was repurposed as the office of the Malaysian Leprosy Relief Society, also serving as the place where beneficiaries collected their monthly relief funds.

In August 2019, it officially became the Valley of Hope Art Gallery, using art as a medium to integrate leprosy survivors with mainstream society. Amateur artists, who are leprosy survivors, depict their isolated years through artistic creations, showcasing their journey from societal rejection and loss of hope to later regaining health and reclaiming self-esteem.

In 2017, the "Art from the Heart of Hope" initiative was launched by gallery director Chen Yanni, auctioning watercolor paintings created by the residents online, receiving positive feedback. Leprosy survivors regained confidence, tapped into their latent artistic potential, and ignited a desire to help others, producing a large number of artworks fueled by imagination. The following year, pastel paintings were auctioned, raising a breakthrough amount of funds and earning an invitation to participate in a Malaysian pastel exhibition endorsed by the founder of Japanese pastel. In 2019, the residents' artworks were showcased in the national art gallery, attracting attention from various sectors of the art community. The three consecutive years of online auctions helped raise over 30,000 Malaysian Ringgit, supporting the charitable fund of the Xiantu Temple in Kuala Lumpur.

The "Art from the Heart of Hope" has become an annual event at the art gallery, aiming to raise funds for disadvantaged groups in need of assistance. Currently, the gallery has a hands-on painting corner, welcoming the public to experience the joy of painting.